Cutaneous symptoms of a diseased pancreas:
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The pancreas produces hormones and pancreatic juice - substances we can't live without. Unfortunately, he doesn't warn us when he's in trouble. Find out what skin changes can indicate pancreatic disease.

Purpura as a symptom of pancreatitis:
Necrosis and subcutaneous tissue inflammation may indicate pancreatic cancer:
Migratory erythema and pancreas:
Itchy skin and sick pancreas:
Jaundice is a symptom of pancreatic cancer:
Purpura is a symptom of pancreatitis:
Along with fever, nausea, vomiting, stomach ache and an increase in the level of the pancreatic enzyme - amylase - one of the symptoms indicating acute pancreatitis (ACS). The disease most often occurs as a result of alcohol abuse or due to cholelithiasis. The prognosis for acute pancreatitis depends on many factors, such as age, clinical features, comorbidities and imaging results.
Skin lesions in the form of a mottled rash appear mainly on the lateral surfaces of the trunk and in the navel area, and are the result of the accumulation of hemorrhagic peritoneal fluid in the subcutaneous tissue. In the course of the disease, mottled cyanosis (Walzel's symptom) may also appear in the area of the abdominal wall and trunk.




Read more: Acute and chronic pancreatitis - symptoms, treatment

Necrosis and inflammation of the subcutaneous tissue may indicate pancreatic cancer
Subcutaneous tissue necrosis in the course of pancreatitis most often affects patients between 30 and 40 years of age. Clinically, the eruptions are in the form of tumors or papules with a diameter of about 1-5 cm. They occur primarily on the arms, torso, buttocks, thighs and lower legs. In severe cases, painful bumps spontaneously rupture and leave depressed, discolored scars.

Patients with numerous inflammatory and necrotic eruptions often have a fever, and also complain of abdominal pain and vomiting. Histopathological examination determines the diagnosis of inflammation and necrosis of the subcutaneous tissue. Subcutaneous tissue necrosis may coexist with pancreatic cancer.

Migraine and pancreas
Many benign and malignant pancreatic tumors have the ability to produce and release various hormones that can provoke skin lesions. An example is the so-called migratory erythema that occurs in the case of a glucagonoma tumor (a glucagon-producing pancreatic cancer).

Initially, the lesions have the nature of erythema of varying diameter, and a bladder appears in the central part. After breaking the cover, a necrosis foci is formed, covered with a dark necrotic scab, which heals, leaving a discoloration. Active changes are accompanied by pain and itching.

Skin changes will appear primarily on the limbs, then around the mouth, in the uplifted areas, especially in the perineum and lower abdomen. Efflorescence can mimic eczema, contact dermatitis, thrush, psoriasis or purulent staphylococcal dermatitis. In addition to migratory necrotizing erythema, patients often have symptoms of stomatitis and tongue inflammation.

Itchy skin and sick pancreas:
This is a symptom resulting from the appearance of protein complexes with bilirubin just under the skin - such a specific introduction to jaundice. In most patients, however, it does not show up as a change in skin color due to low bile pigmentation. Itching can be of various severity, chronic, lasting more than six weeks, may be the first signal of an ongoing tumor process.

Jaundice is a symptom of pancreatic cancer:
Jaundice is the yellow coloration of the skin, mucous membranes and the whites of the eyes, caused by excessive bilirubin in the blood serum. Sometimes it may be accompanied by discoloration of the stool and darkening of the urine, as well as itching of the skin. Jaundice is a symptom that occurs in almost 90 percent. patients with pancreatic cancer.

It can be caused by compression of the bile ducts by a tumor (primarily the head of the pancreas or Vater's warts) or by enlarged lymph nodes and obstructions in the flow of bile from the liver to the intestine, as well as damage to the liver by cancer metastases. Both causes can coexist.