I-BioNTech, i-moderna, i-curevac, i-covid-19, i-coronavirus, umgomo:
20200320AD
Ama-BTM Innovations, ukusebenzisana komphakathi kanye nezangasese, i-Apeiron, i-SRI International, i-Iktos, izidakamizwa ezingasebenzi, i-AdaptVac, i-ExpreS2ion Biotechnologies, pfizer, janssen, sanofi,

NgoMashi 16, Ikhomishini YaseYurophu yamemezela ukuthi inikele nge-EUR 80 yezigidi ukuxhasa inkampani yaseJalimane i-CureVac ukusheshisa umsebenzi wokugomela i-coronavirus. Le mininingwane ivela ngosuku ngemuva kwemithombo kahulumeni waseJalimane ethe abaphathi bakaDonald Trump bafuna indlela yokuthola lo mgomo ongaba khona. Ngabe lokhu kusho ukuthi kunenkampani eyodwa kuphela esebenza isisombululo esibaluleke kakhulu esintwini? I-WHO (World Health Organisation) ishicilela imininingwane ezinkampanini ezinjalo eziyi-13 kumawebhusayithi ayo, futhi i-Global Data database ikhombisa izikhungo ezingama-30 ezisebenza ngalesi sihloko. Ngabe akhona amathuba okuthola ikhambi elisheshayo lezinkinga zethu? UDeveli uhlala enemininingwane.
Ngokusemthethweni, kunenkampani eyodwa kuphela - iMelika Moderna - edlulele esigabeni secala lokuhlola lapho umuthi wokugoma uhlolwa khona kubantu. Ukuhlolwa kwenziwa e-United States eWashington Institute of Health Research eSeattle. Ukuthuthuka okusheshayo komjovo okungaba khona bekungakaze kubonwe ngaphambili futhi kungenzeka ngoba ososayensi bangasebenzisa isipiliyoni ngama-coronavirus abangela ubhubhane lwe-SARS kanye ne-MERS. Yize umsebenzi wephula amarekhodi, noma ngabe umuthi wokugomela ubonakala uphephile futhi usebenza ngempumelelo ngokumelene naleli gciwane, ngeke ube khona okungenani unyaka.
Bonke abanye abadlali abafuna ukuthuthukisa umuthi wokugomela i-coronavirus njengamanje basesigabeni esiphakeme kakhulu sokulungiselela. Isigaba sokuqala ukucwaninga ezindaweni zokuhlanza izilwane kanye nezilwane okungaholela ekugomeni esikhathini esingangonyaka nesigamu. Kunzima ukusho ukuthi ngubani ozuza umjaho wokugoma, kodwa amathuba amakhulu akuyona ukuqala kokuqala, kodwa izinkampani ezinkulu zemithi.

Inkampani yaseJalimane iCureVac isebenzisana nesikhungo sikahulumeni esizinze e-Oslo, okuthiwa Umdwebo Wokulungiselela Ubhubhane (I-CEPI). Basebenza umuthi wokugomela osuselwa ku-mRNA. Njenge-American giant Moderna mRNA, iCureVac ifuna ukufakazela ukuthi imijovo ye-mRNA izothuthukiswa futhi yenziwe ngokushesha kunemithi yokugomela yendabuko, futhi ihlose ukuya ezivivinyweni zemitholampilo zesigaba sokuqala ekuqaleni kwehlobo.
NjengeCureVac - inkampani yaseJalimane i-BioNTech, ethuthukisa imigomo yokugomela umkhuhlane we-mRNA ngomdlavuza - iyisihloko sokubambisana okungaba khona nePfizer enkulu yezemithi yokwakha umuthi wokugomela igciwane leCovid19. USanofi noJanssen babambisana ne-American Biomedical Advanced Office for Research and Development (BARDA) futhi basesigabeni sokunqunyelwa.
Amaphrojekthi amaningi amancane nawo ayaqhubeka. NgoMsombuluko2 EUR izigidi ezingama-7 zezimali zomxhaso ngaphansi kohlelo lwe-Horizon2020 zabelwa izinhlangano zomphakathi zaseDenmark: izinkampani ze-biotechnology i-ExpreS2ion Biotechnologies ne-AdaptVac. I-Consortium ihlose ukwethula isivivinyo somtholampilo wesigaba I / IIa sokugomela kungakapheli izinyanga eziyi-12.

Ngenkathi imijovo yakuqala ingaba sesigabeni sokugcina kuze kufike ehlobo, abalawuli cishe bazodinga unyaka owodwa kuya kwemibili wokuhlolwa komuntu ukuze baqiniseke ukuthi umuthi wokugoma uphephile futhi uyasebenza. Ngemuva kokuthola imvume, izinkampani zingaqala ukukhiqiza futhi zisabalalise umuthi wokugomela ngezinga lokuhweba, nakho okuthatha isikhathi eside. Ngokufingqa, umhlaba ubona umuthi wokugomela ovunyelwe we-Covid-19 kuphela maphakathi no-2121.
Kodwa-ke, kuvela ukuthi umuthi wokugoma akuyona ukuphela kwensindiso. Izinkampani eziningi zilindele ukuthuthukisa izidakamizwa ezintsha ze-antiviral noma zihambise izidakamizwa zokuhlola zamanje zokulwa naleli gciwane elisha. Lona ngumsebenzi onzima ngoba, ngokungafani namagciwane, amagciwane afihla emangqamuzaneni ethu. Lokhu kusho ukuthi umuthi ovimba igciwane uvame ukuthinta amaseli ethu, ongadala imiphumela emibi.
Inkampani yaseParisian Iktos esebenza ekukhiqizweni kwezidakamizwa ngobuhlakani bokuqamba yaqala ukusebenzisana nenkampani yamakhemikhali yaseMelika iSRI International. Umgomo wokubambisana ukukhulisa izidakamizwa ezintsha ze-antiviral zokwelapha i-Covid19 kanye nezinye izinhlobo zamagciwane. Inkampani yase-Austrian biotechnology i-Apeiron yaqala isivivinyo semitholampilo yesigaba II somuthi okhethwe yi-Covid-19 ekupheleni kukaFebhuwari. Umuthi wamaprotheni usuvele uqedile izifundo zesigaba sokuqala nesesi-2 ekwelashweni kokulimala kwamaphaphu futhi kulindeleke ukuthi usebenze ngokulingisa iprotheni elihlanganiswe yi-coronavirus ngesikhathi sokuhlasela kwamaphaphu. futhi kunamaphrojekthi amaningi ahlose ukuguqula ukusetshenziswa kwezidakamizwa ezigunyaziwe zokwelapha i-Covid-19. Lokhu kunenzuzo yokuthi ukuphepha komuthi sekuyaziwa futhi kungafinyelela imakethe ngokushesha okukhulu. Abaphenyi baseGöttingen naseBerlin, eJalimane, njengamanje baphenya ukuthi kungenzeka yini ukuthi kune-kamostat mesylate - isidakamizwa esivunyelwe eJapan ukwelapha i-pancreatitis.

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