mRNA-1273: Umuthi wokugomela iCoronavirus ulungele ukuhlolwa emtholampilo:
 
Umuthi wokugomela iCoronavirus ulungele ukuhlolwa emtholampilo
Inkampani ye-Biotechnology Moderna, yaseCambridge, Mass., Imemezele ukuthi umuthi wayo wokugomela, i-mRNA-1273, ngegciwane elisakazeka ngokushesha nge-Covid-19 kungekudala uzoya ezivivinyweni zokwelashwa zaseSigaba 1 e-US. Iqoqo lokuqala lomjovo omusha selivele lathunyelwa kwiNational Institute of Allergy and Inferior Diseases (NIAID).
i-mRNA-1273 yathuthukiswa nguModerna ngokubambisana nabaphenyi be-NIAID Vacccine Research Center (VCR). Umkhiqizo we-batch uxhaswe ngemali yiCoalition for Epidemic Preparedness Inovations (CEPI). Ucwaningo lokuphepha kanye ne-immunogenicity, okumele luqale ngoMashi 6, luzobandakanya abesilisa nabesifazane abangama-45 abanempilo abaneminyaka yobudala eyi-18-55. Ababambiqhaza bazothola umuthi wokugoma ngemithamo engama-25, 100 noma ama-250 e-cicron (okuningi mayelana nocwaningo lapha). U-Anthony Fauci, umqondisi we-NIAID, esitatimendeni seThe Wall Street Journal ukuthi lolu cwaningo kungenzeka luqale ngaphambi kokuphela kuka-Ephreli. Kodwa-ke, kuzothatha inyanga eyodwa kuya kweyi-18 ngaphambi kokuthi umuthi wokugoma ususetshenziswe jikelele.
UJuan Andres, oyiChief Technical Operations and Quality Officer kwa-Moderna, uphawula - Ngithanda ukubonga lonke ithimba leModerna ngomzamo wabo ongaphezu kokuvamile, okuyisisombululo enkingeni yezempilo yomhlaba. Ukubambisana ne-NIAID ne-CEPI kuvumele ukulethwa kwe-batch yomtholampilo kungakapheli izinsuku ezingama-42 kukhonjwa ukulandelana. Ngokusho kwengosi ye- axios.com, uma isimo eChina sesiya ngokuya simbi, kunengozi yokushoda kokulethwa e-US kwemithi engaba ngu-150 kadokotela (kubandakanya imithi elwa namagciwane, i-generics, izidakamizwa ezingenakho ukufaka esikhundleni). Ngokusho kwengosi, le mishanguzo ibekwe ohlwini lwezingcingo e-US Food and Drug Administration (FDA). Yize i-FDA ingasho lutho ngale mibiko, iyagcizelela ukuthi ukusatshalaliswa okuqhubekayo kwe-coronavirus kungathinta impela i-supply chain.
Ibhalansi yamanje yomhlaba we-coronavirus ingaphezulu kwezinkulungwane ezingama-79. onegciwane, ngaphezu kwe-2.6,000 ukufa, iningi elixakile eChina. Ukudlanga kwezifo sekuqinisekisiwe nase-Italy, eSouth Korea nase-Iran. Umuthi wokugomela uhlobo olusha lwe-coronavirus, ngokubambisana nohulumeni wase-US, uyasebenza futhi, phakathi kwabanye UJohnson & Johnson, uRegeneron Pharmaceuticals noSanofi.